The Apothecary Diaries Season 2 is a tV series anime that premiered in winter 2025, produced by TOHO animation STUDIO.

About the production: the story comes from a light novel, there are 24 episodes of about 24 minutes and its current status is "finished".

Its main genres are drama and mystery, with themes such as Medicine, Female Protagonist, Royal Affairs and Detective.

On AniList, The Apothecary Diaries Season 2 has an average score of 88%, one of the highest scores on the site, and appears on 216,453 users' lists.

The franchise continues in or follows from: Kusuriya no Hitorigoto and Kusuriya no Hitorigoto 3rd Season.

Using her wit and vast knowledge of medicines and poisons alike, Maomao played a pivotal role in solving a series of mysteries and conspiracies that plagued the imperial court. Having recently come to terms with the secrets of her parents, she returns to fulfill her normal duties on behalf of the emperor's highest-ranking consorts. Maomao also works alongside the eunuch Jinshi to better the consorts' many ladies-in-waiting, including helping them learn to read. However, with the arrival of a merchant caravan comes a new wave of intrigue. A pattern of strange coincidences involving the visitors and their wares unsettles Maomao, driving her to investigate the puzzling circumstances behind the convoy. As dangers from both outside and within threaten the balance between the imperial concubines, Maomao continues to utilize her cunning and medical expertise to keep the women safe from harm. (Source: MAL Rewrite)

Official synopsis from AniList.