Eyeshield 21 is a tV series anime that premiered in spring 2005, produced by Studio Gallop.

About the production: the story comes from a manga, there are 145 episodes of about 23 minutes and its current status is "finished".

Its main genres are action, comedy and sports, with themes such as American Football, School Club, Male Protagonist and School.

On AniList, Eyeshield 21 has an average score of 76%, a very good score, and appears on 34,612 users' lists.

Welcome to the Gridiron of the Damned! Huge, hulking bodies throw themselves at each other, while a tiny, lithe body runs between them toward the goal! No, it’s not a game of football, it’s Sena Kobayakawa trying to evade the monstrous Ha-Ha brothers down the halls of Deimon High School! But wait! Sena’s incredible skills at not getting caught have been spotted by the devilish (possibly actually demonic) captain of the school’s embryonic American-style football team. When Sena asks to be the team’s manager, he gets thrust onto the field as a running back instead! But there are two BIG catches. First, to keep the identity of their new “star” player an absolute secret, Yoichi makes Sena wear an opaque visor on his helmet and gives him the alias of “Eyeshield 21.” And the second catch? Well, in order to hit his fastest “speed of light” running mode, Sena usually has to be absolutely terrified. Not that THAT will be a problem with the monstrous players that he’ll soon find himself running from! The insanity hits the streets when the feet meet the cleats in Eyeshield 21! (Source: Sentai Filmworks, edited)

Official synopsis from AniList.